Endocrine Abstracts

Introduction: Polycystic ovary syndrome (PCOS) have an increased rate of metabolic syndrome (MS). Many studies have proved that adiponectin is closely associated with MS and participate in the disturbances of gonadal axis. The aim of the study was to evaluate the association of adiponectin levels with MS in PCOS.Patients and methods: Study group included 38 patients with PCOS (Rotterdam criteria) compared to 30 healthy volunteers age and sex matched, all...

Introduction: The association of type 1 diabetes mellitus (DM1) with thyroid diseases is well known, especially in the field of polyglandular autoimmune diseases. Thyroid status can influence the necessary of insulin – decreased in hypothyroidism and higher in hyperthyroidism. We wanted to evaluate the prevalence of thyroid pathology in patient with DM1.Patients and methods: Cross-sectional study including 66 patients with DM1 (23 men, 43 women) age...

Introduction: Usually, the hormonal profile is normal in patients with empty sella. However, when present, hormonal deficiency most commonly consist in growth disturbance in children and mild hyperprolactinaemia in adults. Hypopititarism with signs of symptomatic dysfunction occurs in <10% of patient with primary empty sella.Case report: A 27-years-old man presented to our department in 2008 with impuberism, micropenis, hypoplasic scrotum, inguinal g...

Polycystic ovary syndrome (PCOS) is a heterogeneous condition affecting 5–10% of reproductive -age female population.The aim of this study was to determine the clinical features, metabolic and hormonal profile in obese and overweight women with PCOS.Patients and method: A total of 102 women (age 31.28±6.05 and BMI 33.02±5.93) with PCOS and 110 (age 32.35±4.96 and BMI 33.05±5.87) matched controls were invest...

Hormonal treatment (HT) represents the only complete therapy of the consequences of the postmenopausal estrogenic deficiency. Quality of life in postmenopausal women is often compromised. We evaluated the quality of life (appreciated with IQL questionnaire) in 80 postmenopausal women – 40 with intact uterus, treated with natural estrogens associated with progestin, and 40 non-treated women. Group selection (treated/not treated) was made function of the inform consent of t...

Introduction: Subacute thyroiditis (SAT) is characterized by cervical pain. Rarely, other thyroid diseases, like Hashimoto’s thyroiditis (HT), may be associated with cervical pain, leading to confusions with SAT. We report a particular case of painful goitre.Case report: D Maria, 50 years old, presented with cervical pain, low grade fever, inflammatory syndrome (ESR=132 mm/1 h), and was diagnosed with SAT. Thyroid function was normal. Ultrasound (US...

Introduction: Wolfram syndrome, a very rare condition, is a neurodegenerative disorder characterized by diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) which appear in childhood, hampering diagnosis and treatment. Others less frequent features as hypergonadotropic hypogonadism, microvascular disease and local fibromatosis are reported in a male patient diagnosed at the age of 18 years.Case report: An 18-year-old male patient d...

Medullary thyroid carcinoma (MTC) is a rare tumoral entity related to parafollicular C cells of the thyroid gland, characterized by peculiar morphological, functional and evolutional features. The aim of this study was to characterize the cases of medullary carcinoma diagnosed in a university hospital in a 5 years interval (January 1999–December 2003) and to evaluate the diagnostic methods. In this time interval, from a total of 171 thyroid malignancy, 12 (7%) were medull...